Claude on NVIDIA GB300 Blackwell Ultra in Azure: generally available
freshWhat moved: Anthropic's Claude Sonnet 4.5, Opus 4.1, and Haiku 4.5 are now generally available in Microsoft Foundry, hosted on Azure and running on NVIDIA GB300 NVL72 systems with Quantum-X800 InfiniBand. This extends the November 2025 three-way partnership from preview to production-grade enterprise infrastructure.
Why it matters: This is the first production deployment where Claude runs natively on Blackwell Ultra-class hardware inside a hyperscaler's governed agent platform. NVIDIA and Anthropic are co-engineering at the model-to-silicon boundary (kernels, operator fusion, quantization mapped to tensor cores). Microsoft Foundry provides identity, governance, and the enterprise distribution surface. The NVIDIA Secure Agent Workspace Reference Design gives enterprises a blueprint for running autonomous agents with infrastructure-level credential and network policy control.
Strategic signal: The silicon-cloud-model triad is now the enterprise default. Model-only players face portability questions — models tuned for Blackwell may not yield the same efficiency elsewhere without additional engineering.